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The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA.

We have measured removal of pyrimidine dimers in defined DNA sequences in confluent and actively growing normal human and xeroderma pigmentosum complementation group C (XP-C) fibroblasts exposed to 10 J/m2 UV-irradiation. In normal fibroblasts 45% and 90% of the dimers are removed from the transcrip...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Venema, J, van Hoffen, A, Natarajan, A T, van Zeeland, A A, Mullenders, L H
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1990
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2308842/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.3.443
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