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Binding Site and Affinity Prediction of General Anesthetics to Protein Targets Using Docking

BACKGROUND: The protein targets for general anesthetics remain unclear. A tool to predict anesthetic binding for potential binding targets is needed. In this study, we explore whether a computational method, AutoDock, could serve as such a tool. METHODS: High-resolution crystal data of water soluble...

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Main Authors: Liu, Renyu, Perez-Aguilar, Jose Manuel, Liang, David, Saven, Jeffery G.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334420/
https://ncbi.nlm.nih.gov/pubmed/22392968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31824c4def
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