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Role of Gly117 in the cation/melibiose symport of MelB of Salmonella typhimurium

The melibiose permease of Salmonella typhimurium (MelB(St)) catalyzes symport of melibiose with Na(+), Li(+) or H(+), and bioinformatics analysis indicates that a conserved Gly117 (helix IV) is part of the Na(+)-binding site. We mutated Gly117 to Ala, Pro, Trp or Arg; the effects on melibiose transp...

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Detalles Bibliográficos
Main Authors: Guan, Lan, Jakkula, S. Vivek, Hodkoff, Alexey A., Su, Yue
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334291/
https://ncbi.nlm.nih.gov/pubmed/22413840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300230h
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