Testosterone-induced relaxation of coronary arteries: activation of BK(Ca) channels via the cGMP-dependent protein kinase

Androgens are reported to have both beneficial and detrimental effects on human cardiovascular health. The aim of this study was to characterize nongenomic signaling mechanisms in coronary artery smooth muscle (CASM) and define the ionic basis of testosterone (TES) action. TES-induced relaxation of...

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Hlavní autoři: Deenadayalu, Viju, Puttabyatappa, Yashoda, Liu, Alexander T., Stallone, John N., White, Richard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334243/
https://ncbi.nlm.nih.gov/pubmed/22081702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00046.2011
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