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Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing – a biochemical paradigm for the ageing immune system
It is widely accepted that cell-mediated immune functions decline with age, rendering an individual more susceptible to infection and possibly cancer, as well as to age-associated autoimmune diseases. The exact causes of T-cell functional decline are not known. One possible cause could be the develo...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2003
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333419/ https://ncbi.nlm.nih.gov/pubmed/14680505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1019 |
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