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Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts
Uncoupling between DNA polymerases and helicase activities at replication forks, induced by diverse DNA lesions or replication inhibitors, generate long stretches of primed single-stranded DNA that is implicated in activation of the S-phase checkpoint. It is currently unclear whether nucleation of t...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3333866/ https://ncbi.nlm.nih.gov/pubmed/22187152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1241 |
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