MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patens

The moss Physcomitrella patens is unique among plant models for the high frequency with which targeted transgene insertion occurs via homologous recombination. Transgene integration is believed to utilize existing machinery for the detection and repair of DNA double-strand breaks (DSBs). We undertoo...

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Библиографические подробности
Главные авторы: Kamisugi, Yasuko, Schaefer, Didier G., Kozak, Jaroslav, Charlot, Florence, Vrielynck, Nathalie, Holá, Marcela, Angelis, Karel J., Cuming, Andrew C., Nogué, Fabien
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333855/
https://ncbi.nlm.nih.gov/pubmed/22210882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1272
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