MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patens

The moss Physcomitrella patens is unique among plant models for the high frequency with which targeted transgene insertion occurs via homologous recombination. Transgene integration is believed to utilize existing machinery for the detection and repair of DNA double-strand breaks (DSBs). We undertoo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kamisugi, Yasuko, Schaefer, Didier G., Kozak, Jaroslav, Charlot, Florence, Vrielynck, Nathalie, Holá, Marcela, Angelis, Karel J., Cuming, Andrew C., Nogué, Fabien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333855/
https://ncbi.nlm.nih.gov/pubmed/22210882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1272
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