Exacerbation of collagen induced arthritis by Fcγ receptor targeted collagen peptide due to enhanced inflammatory chemokine and cytokine production

Antibodies specific for bovine type II collagen (CII) and Fcγ receptors play a major role in collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA). Our aim was to clarify the mechanism of immune complex-mediated inflammation and modulation of the disease. CII pre-immunized DBA...

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Detalhes bibliográficos
Main Authors: Szarka, Eszter, Neer, Zsuzsa, Balogh, Péter, Ádori, Monika, Angyal, Adrienn, Prechl, József, Kiss, Endre, Kövesdi, Dorottya, Sármay, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333823/
https://ncbi.nlm.nih.gov/pubmed/22532778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S29749
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