In Vivo Detection of Oxidation-Specific Epitopes in Atherosclerotic Lesions Using Bio-Compatible Mn(II) Molecular Magnetic Imaging Probes

OBJECTIVES: To evaluate the in vivo magnetic resonance (MR) imaging efficacy of manganese (Mn(II)) molecular imaging probes targeted to oxidation-specific epitopes (OSE). BACKGROUND: OSE are critical in the initiation, progression and de-stabilization of atherosclerotic plaques. Gadolinium (Gd(III))...

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Auteurs principaux: Briley-Saebo, Karen C., Hoang, Tuyen, Saeboe, Alexander M., Cho, Young Seok, Ryu, Sung Kee, Volkava, Eugenia, Dickson, Stephen, Leibundgut, Gregor, Weisner, Philipp, Green, Simone, Casanada, Florence, Miller, Yury I., Shaw, Walter, Witztum, Joseph L, Fayad, Zahi A., Tsimikas, Sotirios
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333483/
https://ncbi.nlm.nih.gov/pubmed/22300697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.10.881
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