Induction of a deficiency of steroid delta 4-5 alpha-reductase activity in liver by a porphyrinogenic drug.

The hepatic enzymes that catalyze drug oxidations and the reductive metabolism of steroid hormones to 5alpha-derivatives are localized in membranes of the endoplasmic reticulum. Phenobarbital, which exacerbates acute intermittent porphyria in man, induces drug-oxidizing enzymes in liver. Additionall...

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Detaylı Bibliyografya
Asıl Yazarlar: Kappas, A, Bradlow, H L, Bickers, D R, Alvares, A P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1977
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC333343/
https://ncbi.nlm.nih.gov/pubmed/830660
Etiketler: Etiketle
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