Induction of a deficiency of steroid delta 4-5 alpha-reductase activity in liver by a porphyrinogenic drug.

The hepatic enzymes that catalyze drug oxidations and the reductive metabolism of steroid hormones to 5alpha-derivatives are localized in membranes of the endoplasmic reticulum. Phenobarbital, which exacerbates acute intermittent porphyria in man, induces drug-oxidizing enzymes in liver. Additionall...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Kappas, A, Bradlow, H L, Bickers, D R, Alvares, A P
Format: Artigo
Jezik:Inglês
Izdano: 1977
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC333343/
https://ncbi.nlm.nih.gov/pubmed/830660
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki