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Characterization of antibodies to the insulin receptor: a cause of insulin-resistant diabetes in man.

We have characterized the circulating inhibitor of insulin receptor binding found in several patients with a new syndrome of extreme insulin resistance. The inhibitor is an immunoglobulin by multiple criteria, including precipitation by 33% ammonium sulfate, migration on G-200 Sephadex gel filtratio...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Flier, J S, Kahn, C R, Jarrett, D B, Roth, J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1976
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/993353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108600
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