Translation and stability of human globin mRNA in Xenopus oocytes.

Human globin messenger RNA (mRNA) prepared from erythroid cells of patients with sickle cell anemia has been translated in Xenopus laevis oocytes. Addition of hemin to the injected mRNA causes total globin synthesis to increase and the ratio of alpha- to betas-globin synthesis (alpha/betas ratio) to...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Maniatis, G M, Ramirez, F, Cann, A, Marks, P A, Bank, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1976
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1033208/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108597
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