Translation and stability of human globin mRNA in Xenopus oocytes.

Human globin messenger RNA (mRNA) prepared from erythroid cells of patients with sickle cell anemia has been translated in Xenopus laevis oocytes. Addition of hemin to the injected mRNA causes total globin synthesis to increase and the ratio of alpha- to betas-globin synthesis (alpha/betas ratio) to...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Maniatis, G M, Ramirez, F, Cann, A, Marks, P A, Bank, A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1976
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333313/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1033208/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108597
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