Delivery of Small Interfering RNA by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers

The therapeutic potential of small interfering RNAs (siRNAs) is severely limited by the availability of delivery platforms that protect siRNA from degradation, deliver it to the target cell with high specificity and efficiency, and promote its endosomal escape and cytosolic dispersion. Here we repor...

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Detalhes bibliográficos
Main Authors: Ashley, Carlee E., Carnes, Eric C., Epler, Katharine E., Padilla, David P., Phillips, Genevieve K., Castillo, Robert E., Wilkinson, Dan C., Wilkinson, Brian S., Burgard, Cameron A., Sewell, Robin M., Townson, Jason L., Chackerian, Bryce, Willman, Cheryl L., Peabody, David S., Wharton, Walker, Brinker, C. Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332089/
https://ncbi.nlm.nih.gov/pubmed/22309035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn204102q
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