Delivery of Small Interfering RNA by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers

The therapeutic potential of small interfering RNAs (siRNAs) is severely limited by the availability of delivery platforms that protect siRNA from degradation, deliver it to the target cell with high specificity and efficiency, and promote its endosomal escape and cytosolic dispersion. Here we repor...

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Auteurs principaux: Ashley, Carlee E., Carnes, Eric C., Epler, Katharine E., Padilla, David P., Phillips, Genevieve K., Castillo, Robert E., Wilkinson, Dan C., Wilkinson, Brian S., Burgard, Cameron A., Sewell, Robin M., Townson, Jason L., Chackerian, Bryce, Willman, Cheryl L., Peabody, David S., Wharton, Walker, Brinker, C. Jeffrey
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332089/
https://ncbi.nlm.nih.gov/pubmed/22309035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn204102q
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