Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord

Amorphous mesoporous silica nanoparticles (‘protocells’) that support surface lipid bilayers recently characterized in vitro as carrier constructs for small drug and DNA delivery are reported here as highly biocompatible both in vitro and in vivo, involving the brain and spinal cord following spinal...

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Detalhes bibliográficos
Main Authors: Dengler, Ellen C., Liu, Juewen, Kerwin, Audra, Torres, Sergio, Olcott, Clara M., Bowman, Brandi N., Armijo, Leisha, Gentry, Katherine, Wilkerson, Jenny, Wallace, James, Jiang, Xingmao, Carnes, Eric C., Brinker, C. Jeffrey, Milligan, Erin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013798/
https://ncbi.nlm.nih.gov/pubmed/23517784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.03.009
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