Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord

Amorphous mesoporous silica nanoparticles (‘protocells’) that support surface lipid bilayers recently characterized in vitro as carrier constructs for small drug and DNA delivery are reported here as highly biocompatible both in vitro and in vivo, involving the brain and spinal cord following spinal...

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Hauptverfasser: Dengler, Ellen C., Liu, Juewen, Kerwin, Audra, Torres, Sergio, Olcott, Clara M., Bowman, Brandi N., Armijo, Leisha, Gentry, Katherine, Wilkerson, Jenny, Wallace, James, Jiang, Xingmao, Carnes, Eric C., Brinker, C. Jeffrey, Milligan, Erin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013798/
https://ncbi.nlm.nih.gov/pubmed/23517784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.03.009
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