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Influence of the Carboxy-Terminus of Serum Amyloid A On Protein Oligomerization, Misfolding, and Fibril Formation
The fibrillar deposition of serum amyloid A (SAA) has been linked to the disease amyloid A (AA) amyloidosis. We have used the SAA isoform, SAA2.2, from the CE/J mouse strain, as a model system to explore the inherent structural and biophysical properties of SAA. Despite its non-pathogenic nature in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3332083/ https://ncbi.nlm.nih.gov/pubmed/22448726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201903s |
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