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CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion

Repetitive Ag encounter, coupled with dynamic changes in Ag density and inflammation, imparts phenotypic and functional heterogeneity to memory virus-specific CD8 T cells in persistently infected hosts. For herpesvirus infections, which cycle between latency and reactivation, recent studies demonstr...

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Detalhes bibliográficos
Main Authors: Wilson, Jarad J., Pack, Christopher D., Lin, Eugene, Frost, Elizabeth L., Albrecht, Joshua A., Hadley, Annette, Hofstetter, Amelia R., Tevethia, Satvir S., Schell, Todd D., Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331907/
https://ncbi.nlm.nih.gov/pubmed/22447978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103727
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