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Gene Variants in the Folate-mediated One-carbon Metabolism (FOCM) Pathway as Risk Factors for Conotruncal Heart Defects

We evaluated 35 variants among four folate-mediated one-carbon metabolism pathway genes, MTHFD1, SHMT1, MTHFR, and DHFR as risk factors for conotruncal heart defects. Cases with a diagnosis of single gene disorders or chromosomal aneusomies were excluded. Controls were randomly selected from area ho...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zhu, Huiping, Yang, Wei, Lu, Wei, Etheredge, Analee, Lammer, Edward J, Finnell, Richard, Carmichael, Suzan L., Shaw, Gary
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331895/
https://ncbi.nlm.nih.gov/pubmed/22495907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.35313
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