118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects

BACKGROUND: Folic acid taken in early pregnancy reduces risks for delivering offspring with several congenital anomalies. The mechanism by which folic acid reduces risk is unknown. Investigations into genetic variation that influences transport and metabolism of folate will help fill this data gap....

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Detalhes bibliográficos
Main Authors: Shaw, Gary M, Lu, Wei, Zhu, Huiping, Yang, Wei, Briggs, Farren BS, Carmichael, Suzan L, Barcellos, Lisa F, Lammer, Edward J, Finnell, Richard H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700092/
https://ncbi.nlm.nih.gov/pubmed/19493349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-49
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