118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects

BACKGROUND: Folic acid taken in early pregnancy reduces risks for delivering offspring with several congenital anomalies. The mechanism by which folic acid reduces risk is unknown. Investigations into genetic variation that influences transport and metabolism of folate will help fill this data gap....

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Autori principali: Shaw, Gary M, Lu, Wei, Zhu, Huiping, Yang, Wei, Briggs, Farren BS, Carmichael, Suzan L, Barcellos, Lisa F, Lammer, Edward J, Finnell, Richard H
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700092/
https://ncbi.nlm.nih.gov/pubmed/19493349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-49
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