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On-the-Resin N-Terminal Modification of Long Synthetic Peptides

Here we present a highly efficient protocol for on-the-resin coupling of fluorescent dyes or other functional groups to the N-termini of synthetic peptides prior to cleavage and deprotection. The protocol avoids expensive pre-activated dyes and instead employs carboxylated dyes activated by large am...

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書目詳細資料
Main Authors: Stahl, Patrick J., Cruz, Juan C., Li, Yang, Yu, S. Michael, Hristova, Kalina
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331795/
https://ncbi.nlm.nih.gov/pubmed/22387389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.02.032
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