GLUT4 and Glycogen Synthase Are Key Players in Bed Rest–Induced Insulin Resistance

To elucidate the molecular mechanisms behind physical inactivity–induced insulin resistance in skeletal muscle, 12 young, healthy male subjects completed 7 days of bed rest with vastus lateralis muscle biopsies obtained before and after. In six of the subjects, muscle biopsies were taken from both l...

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Detalhes bibliográficos
Main Authors: Biensø, Rasmus S., Ringholm, Stine, Kiilerich, Kristian, Aachmann-Andersen, Niels-Jacob, Krogh-Madsen, Rikke, Guerra, Borja, Plomgaard, Peter, van Hall, Gerrit, Treebak, Jonas T., Saltin, Bengt, Lundby, Carsten, Calbet, Jose A.L., Pilegaard, Henriette, Wojtaszewski, Jørgen F.P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331744/
https://ncbi.nlm.nih.gov/pubmed/22403297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0884
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