GLUT4 and Glycogen Synthase Are Key Players in Bed Rest–Induced Insulin Resistance

To elucidate the molecular mechanisms behind physical inactivity–induced insulin resistance in skeletal muscle, 12 young, healthy male subjects completed 7 days of bed rest with vastus lateralis muscle biopsies obtained before and after. In six of the subjects, muscle biopsies were taken from both l...

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Hlavní autoři: Biensø, Rasmus S., Ringholm, Stine, Kiilerich, Kristian, Aachmann-Andersen, Niels-Jacob, Krogh-Madsen, Rikke, Guerra, Borja, Plomgaard, Peter, van Hall, Gerrit, Treebak, Jonas T., Saltin, Bengt, Lundby, Carsten, Calbet, Jose A.L., Pilegaard, Henriette, Wojtaszewski, Jørgen F.P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2012
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331744/
https://ncbi.nlm.nih.gov/pubmed/22403297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0884
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