Cystinosis. Intracellular cystine depletion by aminothiols in vitro and in vivo.

Certain aminothiols rapidly deplete cultured cystinotic skin fibroblasts of their abnormally high free (nonprotein) cystine pool. The free cystine content of these cells if reduced by over 90% in 1 h with 0.1 mM cysteamine. This is more rapid than previously known methods of removing free cystine fr...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Thoene, J G, Oshima, R G, Crawhall, J C, Olson, D L, Schneider, J A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1976
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333169/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/932205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108448
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