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Immune responses to the cleavage-associated neoantigens of fibrinogen in man. Identification and characterization of humoral antibodies specific for cleavage fragments.

Cleavage of human fibrinogen and fibrin by plasmin is associated with modification of native antigenic expression and the exposure of cleavage-associated neoantigenic sites on the derivative molecular fragments. In this study, the presence of humoral antibodies in man to cleavage-associated neoantig...

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Pubblicato in:J Clin Invest
Autori principali: Plow, E F, Edgington, T S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1975
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333129/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/53241/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108232
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