MHC2-SCALE enhances identification of immunogenic neoantigens

Summary: Recent studies suggest that CD4+ T cells can exert potent anti-tumor effects and improve immunotherapy efficacy by aiding CD8+ T cells. However, characterizing the mechanism of CD4+ T cells’ anti-tumor activity has been challenging due to inaccurate major histocompatibility complex class II...

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Bibliografske podrobnosti

Principais autores:	Joshua G. Gober, Aude-Hélène Capietto, Reyhane Hoshyar, Martine Darwish, Richard Vandlen, Jonathan L. Linehan, Lélia Delamarre, Adel M. ElSohly
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-04-01
Serija:	iScience
Teme:	Biological sciences Biochemistry methods Immunology Proteomics
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2589004225004730
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