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On the Mechanism of Lithium-Induced Diabetes Insipidus in Man and the Rat

The mechanism of lithium-induced diabetes insipidus was investigated in 96 patients and in a rat model. Polydipsia was reported by 40% and polyuria (more than 3 liter/day) by 12% of patients receiving lithium. Maximum concentrating ability after dehydration and vasopressin was markedly impaired in 1...

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Publicat a:J Clin Invest
Autors principals: Forrest, John N., Cohen, Alan D., Torretti, Jorge, Himmelhoch, Jonathan M., Epstein, Franklin H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1974
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4360856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107649
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