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Effect of vasopressin V2-receptor antagonist tolvaptan on syndrome of inappropriate antidiuresis (SIAD) after transsphenoidal pituitary surgery: recovery of measured osmolality

Background: Delayed hyponatremia after pituitary surgery can be treated with the V2-receptor antagonist, oral tolvaptan. We investigated the pharmacological effect of oral tolvaptan against SIAD in patients with hyponatremia after pituitary surgery. Methods: Thirty-nine patients with pituitary adeno...

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Principais autores: Masahiko Tosaka, Rei Yamaguchi, Yutaro Itabashi, Naoto Mukada, Haruka Tsuneoka, Kentaro Takahashi, Shunsuke Nakamura, Takahiko Nakazawa, Yuhei Yoshimoto
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-10-01
coleção:Heliyon
Assuntos:
Tolvaptan
Vasopressin V2-receptor antagonist
Hyponatremia
Pituitary
Surgery
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S240584402202254X
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