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Increased Clearance of Antipyrine and d-Propranolol after Phenobarbital Treatment in the Monkey

The effects of phenobarbital treatment for 12 days on the regional distribution of blood flow and on the disposition of two model drugs, antipyrine and d-propranolol, have been determined in six unanesthetized rhesus monkeys. Phenobarbital significantly increased total hepatic blood flow from 179±15...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Branch, Robert A., Shand, David G., Wilkinson, Grant R., Nies, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4205524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107647
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