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Increased Clearance of Antipyrine and d-Propranolol after Phenobarbital Treatment in the Monkey: RELATIVE CONTRIBUTIONS OF ENZYME INDUCTION AND INCREASED HEPATIC BLOOD FLOW

The effects of phenobarbital treatment for 12 days on the regional distribution of blood flow and on the disposition of two model drugs, antipyrine and d-propranolol, have been determined in six unanesthetized rhesus monkeys. Phenobarbital significantly increased total hepatic blood flow from 179±15...

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Bibliografski detalji
Glavni autori: Branch, Robert A., Shand, David G., Wilkinson, Grant R., Nies, Alan S.
Format: Artigo
Jezik:Inglês
Izdano: 1974
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC333095/
https://ncbi.nlm.nih.gov/pubmed/4205524
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