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Neutral Proteases and Cathepsin D in Human Articular Cartilage

Proteolytic enzymes have been studied in extracts of human articular cartilage by the use of micromethods. The digestion of hemoglobin at pH 3.2 and of cartilage proteoglycan at pH 5 was shown to be due chiefly to cathepsin D. Cathepsin D was purified 900-fold from human patellar cartilage. Its iden...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Sapolsky, Asher I., Howell, David S., Woessner, J. Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4273625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107641
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