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Translational Control of Hemoglobin Synthesis in Thalassemic Bone Marrow

Previous studies of β-thalassemic reticulocytes have implied a decreased amount of functional β-mRNA but unimpaired translation of the β-mRNA present. However, the β/α synthetic ratios in β-thalassemic marrow are higher than those observed in reticulocytes of the same patients. This could imply that...

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Autores principales: Cividalli, Gabriel, Nathan, David G., Lodish, Harvey F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1974
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC333079/
https://ncbi.nlm.nih.gov/pubmed/4815086
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