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Translational Control of Hemoglobin Synthesis in Thalassemic Bone Marrow

Previous studies of β-thalassemic reticulocytes have implied a decreased amount of functional β-mRNA but unimpaired translation of the β-mRNA present. However, the β/α synthetic ratios in β-thalassemic marrow are higher than those observed in reticulocytes of the same patients. This could imply that...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Cividalli, Gabriel, Nathan, David G., Lodish, Harvey F.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1974
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333079/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4815086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107661
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