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Long-term sensitization of mechanosensitive and -insensitive afferents in mice with persistent colorectal hypersensitivity

Afferent input contributes significantly to the pain and colorectal hypersensitivity that characterize irritable bowel syndrome. In the present study, we investigated the contributions of mechanically sensitive and mechanically insensitive afferents (MIAs; or silent afferents) to colorectal hypersen...

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Autori principali: Feng, Bin, La, Jun-ho, Schwartz, Erica S., Tanaka, Takahiro, McMurray, Timothy P., Gebhart, G. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330779/
https://ncbi.nlm.nih.gov/pubmed/22268098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00490.2011
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