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Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice

Lipid droplets in the liver are coated with the perilipin family of proteins, notably adipocyte differentiation-related protein (ADRP) and tail-interacting protein of 47 kDa (TIP47). ADRP is increased in hepatic steatosis and is associated with hyperlipidemia, insulin resistance, and glucose intoler...

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Hlavní autoři: Carr, Rotonya M., Patel, Rajesh T., Rao, Vandana, Dhir, Ravindra, Graham, Mark J., Crooke, Rosanne M., Ahima, Rexford S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330768/
https://ncbi.nlm.nih.gov/pubmed/22378776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00177.2011
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