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BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis

We show that when telencephalic neural progenitors are briefly exposed to bone morphogenetic protein 2 (BMP2) in culture, their developmental fate is changed from neuronal cells to astrocytic cells. BMP2 significantly reduced the number of cells expressing microtubule-associated protein 2, a neurona...

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Bibliografiske detaljer
Main Authors: Nakashima, Kinichi, Takizawa, Takumi, Ochiai, Wataru, Yanagisawa, Makoto, Hisatsune, Tatsuhiro, Nakafuku, Masato, Miyazono, Kohei, Kishimoto, Tadamitsu, Kageyama, Ryoichiro, Taga, Tetsuya
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC33305/
https://ncbi.nlm.nih.gov/pubmed/11331769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101109698
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