Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

Normal prostate and some malignant prostate cancer (PrCa) cell lines undergo acinar differentiation and form spheroids in three-dimensional (3-D) organotypic culture. Acini formed by PC-3 and PC-3M, less pronounced also in other PrCa cell lines, spontaneously undergo an invasive switch, leading to t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Härmä, V, Knuuttila, M, Virtanen, J, Mirtti, T, Kohonen, P, Kovanen, P, Happonen, A, Kaewphan, S, Ahonen, I, Kallioniemi, O, Grafström, R, Lötjönen, J, Nees, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330266/
https://ncbi.nlm.nih.gov/pubmed/21996742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.396
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados