Transient Activation of P38 MAP Kinase and Up-regulation of Pim-1 Kinase in Cardiac Hypertrophy Despite No Activation of AMPK

AMP-activated protein kinase (AMPK), is an important regulator of cardiac metabolism, but it’s role is not clearly understood in pressure overload induced hypertrophy. In addition, the relationship between AMPK and other important protein kinases such as p38 MAP kinase, Akt and Pim-1 are unclear. Th...

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Detalhes bibliográficos
Main Authors: Lei, Biao, Chess, David J., Keung, Wendy, O’Shea, Karen M., Lopaschuk, Gary D., Stanley, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330243/
https://ncbi.nlm.nih.gov/pubmed/18639556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.06.008
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