The Caenorhabditis elegans HEN1 Ortholog, HENN-1, Methylates and Stabilizes Select Subclasses of Germline Small RNAs

Small RNAs regulate diverse biological processes by directing effector proteins called Argonautes to silence complementary mRNAs. Maturation of some classes of small RNAs involves terminal 2′-O-methylation to prevent degradation. This modification is catalyzed by members of the conserved HEN1 RNA me...

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Bibliografiska uppgifter
Huvudupphovsmän: Billi, Allison C., Alessi, Amelia F., Khivansara, Vishal, Han, Ting, Freeberg, Mallory, Mitani, Shohei, Kim, John K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330095/
https://ncbi.nlm.nih.gov/pubmed/22548001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002617
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