Differential Impact of the HEN1 Homolog HENN-1 on 21U and 26G RNAs in the Germline of Caenorhabditis elegans

RNA interference (RNAi)–related pathways affect gene activity by sequence-specific recruitment of Ago proteins to mRNA target molecules. The sequence specificity of this process stems from small RNA (sRNA) co-factors bound by the Ago protein. Stability of sRNA molecules in some pathways is in part r...

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Main Authors: Kamminga, Leonie M., van Wolfswinkel, Josien C., Luteijn, Maartje J., Kaaij, Lucas J. T., Bagijn, Marloes P., Sapetschnig, Alexandra, Miska, Eric A., Berezikov, Eugene, Ketting, René F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400576/
https://ncbi.nlm.nih.gov/pubmed/22829772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002702
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