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A Specific α(5)β(1) Integrin Conformation Promotes Directional Integrin Translocation and Fibronectin Matrix Formation
Integrin adhesion receptors are structurally dynamic proteins that adopt a number of functionally relevant conformations. We have produced a conformation-dependent anti-α(5) monoclonal antibody (SNAKA51) that converts α(5)β(1) into a ligand-competent form and promotes fibronectin binding. In adheren...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329624/ https://ncbi.nlm.nih.gov/pubmed/15615773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.01623 |
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