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Did Clinical Trials in Which Erythropoietin Failed to Reduce Acute Myocardial Infarct Size Miss a Narrow Therapeutic Window?

BACKGROUND: To test a hypothesis that in negative clinical trials of erythropoietin in patients with acute myocardial infarction (MI) the erythropoietin (rhEPO) could be administered outside narrow therapeutic window. Despite overwhelming evidence of cardioprotective properties of rhEPO in animal st...

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Detalhes bibliográficos
Main Authors: Talan, Mark I., Ahmet, Ismayil, Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329541/
https://ncbi.nlm.nih.gov/pubmed/22529941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034819
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