Role of Serine Racemase in Behavioral Sensitization in Mice after Repeated Administration of Methamphetamine

BACKGROUND: The N-methyl-D-aspartate (NMDA) receptors play a role in behavioral abnormalities observed after administration of the psychostimulant, methamphetamine (METH). Serine racemase (SRR) is an enzyme which synthesizes D-serine, an endogenous co-agonist of NMDA receptors. Using Srr knock-out (...

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Hauptverfasser: Horio, Mao, Kohno, Mami, Fujita, Yuko, Ishima, Tamaki, Inoue, Ran, Mori, Hisashi, Hashimoto, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329469/
https://ncbi.nlm.nih.gov/pubmed/22530033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035494
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