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The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake

Cytosolic lipid droplets (LDs) are storage organelles for neutral lipids derived from endogenous metabolism. Acyl-CoA synthetase family proteins are essential enzymes in this biosynthetic pathway, contributing activated fatty acids. Fluorescence microscopy showed that ACSL3 is localized to the endop...

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Bibliografiske detaljer
Main Authors: Poppelreuther, Margarete, Rudolph, Berenice, Du, Chen, Großmann, Regina, Becker, Melanie, Thiele, Christoph, Ehehalt, Robert, Füllekrug, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329388/
https://ncbi.nlm.nih.gov/pubmed/22357706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M024562
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