Demyelinating Diseases: Myeloperoxidase as an Imaging Biomarker and Therapeutic Target

PURPOSE: To evaluate myeloperoxidase (MPO) as a newer therapeutic target and bis-5-hydroxytryptamide-diethylenetriaminepentaacetate-gadolinium (Gd) (MPO-Gd) as an imaging biomarker for demyelinating diseases such as multiple sclerosis (MS) by using experimental autoimmune encephalomyelitis (EAE), a...

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Main Authors: Forghani, Reza, Wojtkiewicz, Gregory R., Zhang, Yinian, Seeburg, Daniel, Bautz, Benjamin R. M., Pulli, Benjamin, Milewski, Andrew R., Atkinson, Wendy L., Iwamoto, Yoshiko, Zhang, Elizabeth R., Etzrodt, Martin, Rodriguez, Elisenda, Robbins, Clinton S., Swirski, Filip K., Weissleder, Ralph, Chen, John W.
Formato: Artigo
Idioma:Inglês
Publicado: Radiological Society of North America, Inc. 2012
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329272/
https://ncbi.nlm.nih.gov/pubmed/22438365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.12111593
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