Demyelinating Diseases: Myeloperoxidase as an Imaging Biomarker and Therapeutic Target

PURPOSE: To evaluate myeloperoxidase (MPO) as a newer therapeutic target and bis-5-hydroxytryptamide-diethylenetriaminepentaacetate-gadolinium (Gd) (MPO-Gd) as an imaging biomarker for demyelinating diseases such as multiple sclerosis (MS) by using experimental autoimmune encephalomyelitis (EAE), a...

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Hlavní autoři: Forghani, Reza, Wojtkiewicz, Gregory R., Zhang, Yinian, Seeburg, Daniel, Bautz, Benjamin R. M., Pulli, Benjamin, Milewski, Andrew R., Atkinson, Wendy L., Iwamoto, Yoshiko, Zhang, Elizabeth R., Etzrodt, Martin, Rodriguez, Elisenda, Robbins, Clinton S., Swirski, Filip K., Weissleder, Ralph, Chen, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Radiological Society of North America, Inc. 2012
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329272/
https://ncbi.nlm.nih.gov/pubmed/22438365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.12111593
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