Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G

OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic multisystem genetically complex autoimmune disease characterised by the production of autoantibodies to nuclear and cellular antigens, tissue inflammation and organ damage. Genome-wide association studies have shown that variants within the...

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Autors principals: Fernando, Michelle M A, Freudenberg, Jan, Lee, Annette, Morris, David Lester, Boteva, Lora, Rhodes, Benjamin, Gonzalez-Escribano, María Francisca, Lopez-Nevot, Miguel Angel, Navarra, Sandra V, Gregersen, Peter K, Martin, Javier, Vyse, Timothy J
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2012
Matèries:
Basic and Translational Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329227/
https://ncbi.nlm.nih.gov/pubmed/22233601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-200808
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