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Two sides of the same coin: EGFR exon 19 deletions and insertions in lung cancer

Most lung adenocarcinoma-associated Epidermal Growth Factor Receptor (EGFR) mutations confer sensitivity to specific EGFR tyrosine kinase inhibitors. The finding that exon 19 insertion mutations are also sensitive to this class of drugs suggests that testing for these mutations should be performed a...

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Detalhes bibliográficos
Main Authors: Politi, Katerina, Lynch, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329215/
https://ncbi.nlm.nih.gov/pubmed/22317760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3282
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