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Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

Epigenetic and genetic alterations have long been thought of as two separate mechanisms participating in carcinogenesis. A recent outcome of whole exome sequencing of thousands of human cancers has been the unexpected discovery of many inactivating mutations in genes that control the epigenome. Thes...

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Detalhes bibliográficos
Main Authors: You, Jueng Soo, Jones, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396881/
https://ncbi.nlm.nih.gov/pubmed/22789535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.06.008
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