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Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1

Matriptase proteolytic activity must be tightly controlled for normal placental development, epidermal function, and epithelial integrity. Although hepatocyte growth factor activator inhibitor-1 (HAI-1) represents the predominant endogenous inhibitor for matriptase and the protein molar ratio of HAI...

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Autori principali: Xu, Han, Xu, Zhenghong, Tseng, I-Chu, Chou, Feng-Pai, Chen, Ya-Wen, Wang, Jehng-Kang, Johnson, Michael D., Kataoka, Hiroaki, Lin, Chen-Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328841/
https://ncbi.nlm.nih.gov/pubmed/22031598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00344.2011
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